Quantifying synovial inflammation:Emerging imaging techniques

• 作者: Deepak Tripathi Vikas Agarwal
• 来源期刊: 世界风湿病学杂志
• 学科: 医学
• 关键词: SYNOVITIS IMAGING Diffusion TENSOR IMAGING POSITRON emission TOMOGRAPHY COMPUTED TOMOGRAPHY Ultrasound
• 年，卷（期）: 2014,（3）
• 页码范围: 72-79
• 页数: 8页
• 分类号: R

摘要

Imaging techniques to assess synovial inflammation includes radiography,ultrasound,computed tomography,magnetic resonance imaging(MRI)and recently positron emission tomography.The ideal objective of imaging approaches are to quantify synovial inflammation by capturing features such as synovial hyperplasia,neo-angiogenesis and infiltration of immune cells in the synovium.This may enable clinicians to estimate response to therapy by measuring the improvement in the inflammatory signals at the level of synovium.Ultrasound can provide information regarding thickening of the synovial membrane and can reveal increased synovial blood flow using power Doppler technique.Bone marrow edema and synovial membrane thickness on MRI scan may serve as indicators for arthritis progression.Enhancement of the synovium on dynamic contrast MRI may closely mirror the inflammatory activity in the synovium.Diffusion tensor imaging is an advance MRI approach that evaluates the inflammation related to cell infiltration or aggregation in an inflamed synovium.In this review,we summarize the newer imaging techniques and their developments to evaluate synovial inflammation..2014 Baishideng Publishing Group Inc.All rights reserved.