Co-Administration of Risperidone and Sodium Valproate Causing Bilateral Chronic Exertional Lower Leg Compartment Syndrome

• 作者: Muhammad A. Bashir Ravi K. Ray Sudhir Rao
• 来源期刊: 矫形学期刊(英文)
• 学科: 医学
• 关键词: RISPERIDONE COMPARTMENT Syndrome
• 年，卷（期）: jxxqkyw_2014,（4）
• 页码范围: 101-103
• 页数: 3页
• 分类号: R73

摘要

We present the case of a 24-year-old man, who was a keen runner, developing chronic bilateral lower leg compartment syndrome following co-administration of Risperidone and Sodium Valproate. Having had failed medical and physical therapies, he underwent surgical decompression of his more problematic left lower leg compartments. In the interval between sequential fasciotomies, control of his psychiatric symptoms allowed the dose of his Risperidone to be reduced, resulting in a greater exercise tolerance. Ultimately he no longer required the contra-lateral lower leg compartments to be decompressed surgically. He had returned to his original level of activity with no further psychotic episodes.