Giant Cell Tumor： Role of Conservative Treatment

• 作者: Anatolii Diedkov Marija Kukushkina Pavlo Kovalchuk Sergey Bojchuk Viktor Kostyuk
• 来源期刊: 健康科学：英文版
• 学科: 生物学
• 关键词: GIANT CELL tumors CONSERVATIVE treatment denosumab.
• 年，卷（期）: 2014,（8）
• 页码范围: 389-392
• 页数: 4页
• 分类号: Q

摘要

Giant cell tumor is aggressive bone tumor. Surgical treatment is considered to be the only effective method of treatment ofthese tumors. The problem of inoperable patients with giant cell tumors is a challenge. A total of 8 patients had giant cell bone tumorsof pelvis and sacrum. 3 patients were treated by bisphosphonates, radiation therapy and embolization of tumor-nutrient arteries. 5patients received denosumab. The efficiency was assessed according to clinical data and CT scan control. Median follow up is 28months. All 8 patients had reduction of pain intensity. Treatment with denosumab demonstrated more than 30% tumor regression. Allof the patients are in remission.