Radiogenomic imaging-linking diagnostic imaging and molecular diagnostics

• 作者: Mathias Goyen
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: Radiogenomic IMAGING PERSONALIZED MEDICINE DIAGNOSTIC IMAGING
• 年，卷（期）: 2014,（8）
• 页码范围: 519-522
• 页数: 4页
• 分类号: R730.44

摘要

Radiogenomic imaging refers to the correlation between cancer imaging features and gene expression and is one of the most promising areas within science and medicine. High-throughput biological techniques have reshaped the perspective of biomedical research allowing for fast and efficient assessment of the entire molecular topography of a cell’s physiology providing new insights into human cancers. The use of non-invasive imaging tools for gene expression profiling of solid tumors could serve as a means for linking specific imaging features with specific gene expression patterns thereby allowing for more accurate diagnosis and prognosis and obviating the need for high-risk invasive biopsy procedures. This review focuses on the medical imaging part as one of the main drivers for the development of radiogenomic imaging.