With the popularization of vulgarized weaving, dyeing, and printing textiles, design of personalized home textiles based on redesign of fabrics has become a key research topic. The handpainted craft-based secondary fabric design of home textiles enhances artistic charm and additional value of products, brings new ideas to the design, and promotes the innovation of materials. Creative application and development of handpainted craft-based secondary fabric design of home textiles were explored from the perspectives of color theme, fabrics, and painting technique.