2-deoxy-2-(¹⁸F)fluoro-D-glucose positron emission tomography/computed tomography imaging in paediatric oncology

• 作者: Eva A Wegner John Freebody Monica A Rossleigh
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: POSITRON emission TOMOGRAPHY Computed TOMOGRAPHY FLUORODEOXYGLUCOSE F18 PAEDIATRICS On-cology Technical issues Dosimetry
• 年，卷（期）: 2014,（10）
• 页码范围: 741-755
• 页数: 15页
• 分类号: R814.42

摘要

Positron emission tomography(PET) is a minimally in-vasive technique which has been well validated for the diagnosis, staging, monitoring of response to therapy, and disease surveillance of adult oncology patients. Tra-ditionally the value of PET and PET/computed tomogra-phy(CT) hybrid imaging has been less clearly defined for paediatric oncology. However recent evidence has emerged regarding the diagnostic utility of these mo-dalities, and they are becoming increasingly important tools in the evaluation and monitoring of children with known or suspected malignant disease. Important indi-cations for 2-deoxy-2-(18F)fluoro-D-glucose(FDG) PET in paediatric oncology include lymphoma, brain tumours, sarcoma, neuroblastoma, Langerhans cell histiocytosis, urogenital tumours and neurofibromatosis type Ⅰ. This article aims to review current evidence for the use of FDG PET and PET/CT in these indications. Attention will also be given to technical and logistical issues, the description of common imaging pitfalls, and dosimetric concerns as they relate to paediatric oncology.