Hyperthyroidism Due to Papillary Thyroid Carcinoma Associated with Ductal Breast Carcinoma

• 作者: Delcio Scandiuzzi Ilka Mara Borges Botelho Modolo Lilian Carla Silva Luciene Mayumi Sato Marcus Aurelho Lima Maria de Fátima Borges Rodrigo Gimenez Pissutti Modolo Rogério Costa Tiveron
• 来源期刊: 临床医学病理报告(英文)
• 学科: 医学
• 关键词: PAPILLARY CARCINOMA HYPERTHYROIDISM BREAST CARCINOMA THYROID Metastasis
• 年，卷（期）: 2014,（8）
• 页码范围: 479-486
• 页数: 8页
• 分类号: R73

摘要

Thyroid tumors are usually associated with euthyroidism, and hyper functioning tumors are rare. There are few reports of carcinomas associated with hyperthyroidism. The aim of this study is to describe a case of hyper functioning papillary carcinoma associated with breast carcinoma. We present a 46-year-old woman that was referred for investigation of thyroid and breast nodules detected by routine ultrasound. She presented with hyperthyroidism and enlarged left thyroid lobe with fibroelastic consistency. Investigation demonstrated papillary carcinoma with follicular hyperactivity and invasive ductal carcinoma of the breast. The patient developed metastases 6 months later and died. This study demonstrates that hot thyroid nodules may harbor malignant tumors and should be punctured. The association with breast adenocarcinoma and the unfavorable outcome suggest higher aggressiveness of this tumor in the presence of hyperthyroidism.