Primary Cardiac Involvement in Scleroderma and Role of Cardiac MRI

• 作者: Kashif Hussain Robert C. Stansbury
• 来源期刊: 临床医学国际期刊(英文)
• 学科: 医学
• 关键词: SCLERODERMA PRIMARY CARDIAC INVOLVEMENT CARDIAC MRI
• 年，卷（期）: 2014,（20）
• 页码范围: 1316-1319
• 页数: 4页
• 分类号: R5

摘要

Systemic sclerosis (scleroderma) is a connective tissue disease characterized by vascular dysfunction and fibrosis that can affect multiple organ systems. We present case of primary cardiac involvement and the diagnostic role of cardiac MRI. Cardiovascular magnetic resonance imaging (MRI) is an accurate, quantitative method for the non-invasive assessment of myocardial perfusion. The presence of clinically apparent myocardial involvement in scleroderma portends a very poor prognosis. One study of US veterans found that clinical cardiac disease in scleroderma was associated with a 70% mortality rate at five years. Management of heart failure and conduction system abnormalities in scleroderma is similar to other cardiac disease. It includes afterload reduction, beta-blockade, defibrillator placement, etc. Patients with reduced cardiac function and normal coronary arteries may benefit from increased immune suppresion.