Rheumatoid Arthritis with High Serum KL-6 Complicating Malignant Tumor: Two Case Reports

• 作者: Hiroyuki Tsuchie Kana Sasaki Moto Kobayashi Seietsu Senma Seiya Miyamoto Yoichi Kataoka Yoichi Shimada Yuichiro Narita Yuji Hatakeyama
• 来源期刊: 矫形学期刊(英文)
• 学科: 医学
• 关键词: KL-6 MALIGNANT Tumor RHEUMATOID ARTHRITIS SP-D
• 年，卷（期）: jxxqkyw_2015,（3）
• 页码范围: 41-45
• 页数: 5页
• 分类号: R5

摘要

Interstitial pneumonia develops not only as a rheumatoid arthritis (RA) manifestation, but also due to the side effects of drugs for its treatment, leading to the necessity of regular examinations. Krebs von den Lungen-6 (KL-6) is often used to check the activity of interstitial pneumonia in RA patients. However, this marker is also produced by some malignant tumors, and a high level of serum KL-6 has been reported in cancer patients. We describe herein 2 cases of RA with the complication of a malignant tumor not involving the lung, although there is no lesion in the lung regardless of the high level of serum KL-6.