Mapping the EQ-5D-5L Utility Scores: A Pilot Study in Orthopaedic Patients

• 作者: Christine Cheng Jerry Bounsanga Man Hung Shirley D. Hon
• 来源期刊: 矫形学期刊(英文)
• 学科: 医学
• 关键词: PROMIS LE CAT Physical Function Depression PAIN EQ-5D-5L ORTHOPAEDICS
• 年，卷（期）: 2015,（4）
• 页码范围: 67-81
• 页数: 15页
• 分类号: R73

摘要

Objective: The purpose of this study is to investigate whether the LE CAT, PROMIS PF CAT, Depression CAT, or Pain CAT can be used as a proxy for the EQ-5D-5L. Background: Patient-reported out-come measures have become vital tools for physicians to understand the effectiveness and value of treatment and care. Methods: This study was conducted in 2012 with 116 patients that took the EQ-5D-5L and a number of patient-reported outcome instruments in a university orthopaedic clinic. Regression analyses were conducted to predict EQ-5D-5L index scores from the LE CAT, PROMIS PF CAT, Depression CAT, and Pain CAT. Results: All predictors, separately or combined, significantly predicted the EQ-5D-5L index scores (p < 0.0001). The LE CAT was the best predictor;it alone accounted for 37% of the variability in the EQ-5D-5L. When combining patient-reported outcome measures, the best predicting model was the one consisting of the LE CAT, Depression CAT and Pain CAT;they explained for 43.9% of the variance in EQ-5D-5L. Conclusions: The findings provide encouraging news that the LE CAT, PF CAT, Depression CAT and Pain CAT can be used alone or in combination as a proxy for the EQ-5D-5L. Researchers have the options of using these patient-reported outcome measures for economic evaluations and medical intervention studies.