Modern Probe-Assisted Methods for the Specific Detection of Bacteria

• 作者: Arghavan Shabani Christophe A. Marquette Marcus F. Lawrence Rosemonde Mandeville
• 来源期刊: 生物医学工程(英文)
• 学科: 医学
• 关键词: BACTERIA Detection Probes Optical PIEZOELECTRIC and ELECTROCHEMICAL Biosensors
• 年，卷（期）: swyxgcyw,（2）
• 页码范围: 104-121
• 页数: 18页
• 分类号: R73

摘要

This review intends to present an overview of methods currently under development for the specific and sensitive detection of pathogenic bacteria that exist in a variety of human environments. Bacteria continue to be a major health threat in general, and much effort is being deployed to counteract this problem. In a first instance, current and efficient techniques in use for the detection of bacteria are described. In a second instance, this review serves to compare the more conventional techniques to emerging technologies for the direct (non-labelled) detection of bacteria (referred to as “biosensors”). These approaches are mainly optical, piezoelectric, and electro-chemical in nature. They are cost-effective, quite sensitive, and potentially portable for rapid on-site/real-time detection, and rapid prevention. These devices are comprised of specific chemical/ biochemical probes immobilized onto physical transducers. This work also presents comparisons between the efficiencies (assay time and sensitivity) of various techniques being employed.