Background: Primary cutaneous tuberculosis is a relatively uncommon manifestation especially in immunocompetent patients and it may occur in countries where tuberculosis is endemic. Findings: In this report, we described a case of a 20-year-old male presenting ulcerative lesions in the left foot and in the right hand caused by Mycobacterium tuberculosis without past history of pulmonary tuberculosis. Conclusion: This case report emphasizes the importance to suspect of a tuberculosis infection in all patients with skin lesions who do not respond to antibiotic treatment.