One-Pot Three Component Domino Reaction for the Synthesis of Novel Isoxazolo[2,3-<i>c</i>][1,3,5]Thiadiazepin-2-Ones Catalyzed by <i>PTSA</i>—A Green Chemistry Approach

• 作者: Eligeti Rajanarendar Kammari Thirupathaiah Kundur Govardhan Reddy Paka Venkateshwarlu Saini Rama Krishna
• 来源期刊: 绿色与可持续化学(英文)
• 学科: 化学
• 关键词: MULTI-COMPONENT Green Synthesis Isoxazolo[2 3-c][1 3 5]Thiadiazepin-2-Ones PTSA
• 年，卷（期）: 2015,（3）
• 页码范围: 107-114
• 页数: 8页
• 分类号: O6

摘要

The synthesis of novel isoxazolo[2,3-c][1,3,5]thiadiazepin-2-ones has been achieved in excellent yields by one-pot three-component Domino reaction without the production of toxic waste products by using p-toluene sulfonic acid (PTSA) as a Lewis acid catalyst. PTSA plays a crucial role in the success of the reaction, as well as for increasing reaction rate.