Clinical implication of hematological indices in the essential hypertension

• 作者: Ahmet Karabulut Aytac Karadag
• 来源期刊: 世界高血压杂志
• 学科: 医学
• 关键词: HYPERTENSION INFLAMMATION End-organ damage Haematological indice PLATELET activation
• 年，卷（期）: 2015,（2）
• 页码范围: 93-97
• 页数: 5页
• 分类号: R

摘要

Prognostic value of haematological indices,especially red cell distribution width,neutrophil lymphocyte ratio and mean platelet volume,was reported with numerous investigations in miscellaneous cardiovascular settings.Their major prognostic value was linked to oxidative stress and inflammation since their level was correlated with major inflammatory markers such as high sensitive C-reactive protein and interleukins.Oxidative stress and chronic inflammation are also postulated as the main pathophysiologic mechanism of essential hypertension(HT)and its vascular complication.Recently,correlation between HT and haematological parameters was searched in numerous studies,which has made the topic more popular.Herein,we reveal the correlation between haematological indices and HT and we also demonstrate the clinical implication of this correlation.Impaired haematological parameters may strongly indicate hypertensive end-organ damage.