New Method for Preparation of 1-Amidoalkyl-2-Naphthols via Multicomponent Condensation Reaction Utilizing Tetrachlorosilane under Solvent Free Conditions

• 作者: Ahmed M. Sheta Mohammad M. A. Mashaly Saad S. Elmorsy Samy B. Said
• 来源期刊: 有机化学国际期刊(英文)
• 学科: 化学
• 关键词: 1-Amidoalkyl-2-Naphthol Tetrachlorosilane (TCS) MULTICOMPONENT REACTION
• 年，卷（期）: yjhxgjqkyw_2015,（3）
• 页码范围: 191-199
• 页数: 9页
• 分类号: O6

摘要

An efficient and direct procedure for the synthesis of amidoalkylnaphthol derivatives employing a multi-component and one-pot condensation reaction of 2-naphthol, aromatic aldehyde and ace-tonitrile in the presence of tetrachlorosilane (TCS). A binary reagent from (TCS)/ZnCl2 was used upon applying benzonitrile.