Collagenous gastritis： Review

• 作者: Kenya Kamimura Masaaki Kobayashi Shuji Terai Yuichi Sato Yutaka Aoyagi
• 来源期刊: 世界胃肠内镜杂志：英文版（电子版）
• 学科: 医学
• 关键词: COLLAGENOUS GASTRITIS COLLAGEN DEPOSITION COLLAGENOUS COLITIS NODULARITY
• 年，卷（期）: 2015,（3）
• 页码范围: 265-273
• 页数: 9页
• 分类号: R

摘要

Collagenous gastritis is a rare disease characterizedby the subepithelial deposition of collagen bandsthicker than 10 μm and the infiltration of inflammatorymononuclear cells in the lamina propria. Collagenouscolitis and collagenous sprue have similar histologicalcharacteristics to collagenous gastritis and are thoughtto be part of the same disease entity. However, whilecollagenous colitis has become more common inthe field of gastroenterology, presenting with clinicalsymptoms of chronic diarrhea in older patients,collagenous gastritis is rare. Since the disease was firstreported in 1989, only 60 cases have been documentedin the English literature. No safe and effective treatmentshave been identified from randomized, controlled trials.Therefore, better understanding of the disease and thereporting of more cases will help to establish diagnosticcriteria and to develop therapeutic strategies. Therefore,here we review the clinical characteristics, endoscopicand histological findings, treatment, and clinical outcomesfrom case reports and case series published to date,and provide a summary of the latest information on thedisease. This information will contribute to improvedknowledge of collagenous gastritis so physicians canrecognize and correctly diagnose the disease, and willhelp to develop a standard therapeutic strategy forfuture clinical trials.