Middle cerebellar peduncles:Magnetic resonance imaging and pathophysiologic correlate

• 作者: Humberto Morales Thomas Tomsick
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: Middle CEREBELLAR PEDUNCLE Brachium pontis Magnetic resonance imaging Multiple sclerosis Progressive MULTIFOCAL LEUKOENCEPHALOPATHY Posterior reversible ENCEPHALOPATHY Toxic ENCEPHALOPATHY
• 年，卷（期）: 2015,（12）
• 页码范围: 438-447
• 页数: 10页
• 分类号: R741

摘要

We describe common and less common diseases that can cause magnetic resonance signal abnormalities of middle cerebellar peduncles(MCP), offering a systematicapproach correlating imaging findings with clinical clues and pathologic mechanisms. Myelin abnormalities, different types of edema or neurodegenerative processes, can cause areas of abnormal T2 signal, variable enhancement, and patterns of diffusivity of MCP. Pathologies such as demyelinating disorders or certain neurodegenerative entities(e.g., multiple system atrophy or fragile X-associated tremor-ataxia syndrome) appear to have predilection for MCP. Careful evaluation of concomitant imaging findings in the brain or brainstem; and focused correlation with key clinical findings such as immunosuppression for progressive multifocal leukoencephalopahty; hypertension, post-transplant status or high dose chemotherapy for posterior reversible encephalopathy; electrolyte disorders for myelinolysis or suspected toxic-drug related encephalopathy; would yield an appropriate and accurate differential diagnosis in the majority of cases.