Protective Role of Golden Flaxseed (<i>Linum usitatissimum</i>L.) Against Oxidative Damage in Lipids and Proteins of Healthy Volunteers

• 作者: Aline Augusti Boligon Bruna Cocco Pilar Jonathaline Apollo Duarte Juliana Mezzomo Leandro Leal Galar?a Luísa Zuravski Manoelly Oliveira Rocha Margareth Linde Athayde Michel Mansur Machado Ritiele Pinto Coelho Vanusa Manfredini
• 来源期刊: 生物科学与医学(英文)
• 学科: 医学
• 关键词: GOLDEN FLAXSEED Grains ANTIOXIDANT Oxidative Damage
• 年，卷（期）: 2015,（10）
• 页码范围: 45-53
• 页数: 9页
• 分类号: R73

摘要

Flaxseed (Linum usitatissimum L.) is composed mainly of bioactive components such as polyphenols, polyunsaturated fatty acids, fiber and lignans. Flaxseed can be found in different presentation forms (grain or flour) and varieties (brown or golden);however, questions have arisen as to whether the presentation form and/or variety may influence the health effects. The objective of this study was to evaluate the effects on blood pressure, anthropometric and oxidative parameters in healthy human volunteers. All subjects received 40 gram aliquots of flaxseed and were instructed to consume them in their entirety mixed with water in the morning for a period of 14 days. Oxidative parameters showed significant reductions (p < 0.05) in oxidative damage to lipids and proteins via dietary intervention with golden flaxseed grains. There were no significant differences in anthropometric parameters, blood pressure, DNA damage and micronuclei frequency after 14-day supplementation. This research indicates that golden flaxseed grains can be a valuable adjunct for disease prevention and protecting the organism against oxidative damage.