Effect of Selective Medicinal Plant Extract on Blood Glucose, Sperm Shape and Various Physiological Parameters

• 作者: Hadeel Khalifa Al-Issaei Ibtisam Saif Al-Neeri Salla Hemadri Reddy Sara Mohammed Al-Jabri
• 来源期刊: 美国植物学期刊(英文)
• 学科: 医学
• 关键词: PHYTOCHEMICAL Screening Blood SUGAR Level SPERM SHAPE PHYSIOLOGICAL Changes
• 年，卷（期）: 2015,（8）
• 页码范围: 1109-1115
• 页数: 7页
• 分类号: R2

摘要

Salvadora persica, Moringa pergrina and Citrullus colocynthis are three traditional important medicinal species used in indigenous medicinal herbal drugs to cure various diseases in South Asia and Middle East countries. The objective of the present study is to investigate the effects of oral administration of extracts of Salvadora persica leaves, Moringa pergrina leaves and Citrullus colocynthis seeds on different physiological parameters of mice. The leaves of Salvadora persica, Moringa pergrina and Citrullus colocynthis seeds were collected from Ibri and Al-Musanaa, dried and crushed into powder and extract was obtained by soxhalet apparatus. The extract was then administered to mice at a dosage of 0.5%, 1.0%, 1.5% and 2.0% for twenty one days. The mice treated with different concentrations of plant extracts showed different physiological changes, Salvadora persica leaf extract at 1.5% and 2.0% showed hypo activity, grooming, prostration, while mice treated with 0.5% and 1.0% showed no effective behavioral changes. The Moringa pergrina leaf extract dosage of 0.5%, 1.0%, 1.5% and 2.0% produced significant weight loss and affected the blood sugar level. Citrullus colocynthis seed extract at 1.5% and 2.0% showed abnormal sperms shape like circular head, double head and double tails whereas at 0.5% and 1.0% exhibited normal sperm shape.