Development of the anterior-posterior axis is a self-organizing process in the absence of maternal cues in the mouse embryo
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摘要:
Dear Editor,
Establishment of the anterior-posterior (AP) axis in the mouse embryo is crucial for proper induction of the germ layers.Despite this importance, it is unclear whether specification of the AP axis is an autonomous process or if it requires an embryonic-maternal interaction atthe time of implantation.