Drug eluting biliary stents to decrease stent failure rates： Areview of the literature

• 作者: J Marc Pipas Jennifer Saad Jisoo Kim Joseph Shatzel Kabir Mody Kartik Sampath Richard I Rothstein Sharjeel Syed Stuart Gordon Timothy Gardner Zilla H Hussain
• 来源期刊: 世界胃肠内镜杂志：英文版（电子版）
• 学科: 医学
• 关键词: BILE ducts CHOLANGIOCARCINOMA ENDOSCOPY PANCREAS
• 年，卷（期）: 2016,（2）
• 页码范围: 77-85
• 页数: 9页
• 分类号: R

摘要

Biliary stenting is clinically effective in relieving bothmalignant and non-malignant obstructions. However, thereare high failure rates associated with tumor ingrowth andepithelial overgrowth as well as internally from biofilmdevelopment and subsequent clogging. Within the lastdecade, the use of prophylactic drug eluting stents as ameans to reduce stent failure has been investigated. Inthis review we provide an overview of the current researchon drug eluting biliary stents. While there is limited humantrial data regarding the clinical benefit of drug elutingbiliary stents in preventing stent obstruction, recentresearch suggests promise regarding their safety andpotential efficacy.