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摘要:
Lesions of the brainstem have been reported in the clinical scenarios of hypoxic-ischemic encephalopathy(HIE), although the prevalence of these lesions is probably underestimated. Neuropathologic studies have demonstrated brainstem involvement in severely asphyxiated infants as an indicator of poor outcome. Among survivors to HIE, the most frequent clinical complaints that may be predicted by brainstem lesions include feeding problems, speech, language and communication problems and visual impairments. Clinical series, including vascular and metabolic etiologies, have found selective involvement of the brainstem with the demonstration of symmetric bilateral columnar lesions of the tegmentum. The role of brainstem lesions in HIE is currently a matter of debate, especially when tegmental lesions are present in the absence of supratentorial lesions. Differential diagnosis of tegmental lesions in neonates and infants include congenital metabolic syndromes and drug-related processes. Brainstem injury with the presence of supratentorial lesions is a predictor of poor outcome and high rates of mortality and morbidity. Further investigation will be conducted to identify specific sites of the brainstem that are vulnerable to hypoxic-ischemic and toxic-metabolic insults.
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篇名 Brainstem tegmental lesions in neonates with hypoxicischemic encephalopathy: Magnetic resonance diagnosis and clinical outcome
来源期刊 世界放射学杂志:英文版(电子版) 学科 医学
关键词 Magnetic resonance ASPHYXIA Hypoxicischemic ENCEPHALOPATHY TEGMENTUM NEONATES BRAINSTEM
年,卷(期) 2016,(2) 所属期刊栏目
研究方向 页码范围 117-123
页数 7页 分类号 R742
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Magnetic
resonance
ASPHYXIA
Hypoxicischemic
ENCEPHALOPATHY
TEGMENTUM
NEONATES
BRAINSTEM
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研究去脉
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期刊影响力
世界放射学杂志:英文版(电子版)
月刊
1949-8470
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
785
总下载数(次)
1
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0
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