Antimicrobial technology in orthopedic and spinal implants

• 作者: Adam EM Eltorai Alan H Daniels Bielinsky A Brea Christopher T Born Dioscaris R Garcia Jack Haglin Roy Ruttiman Sudheesha Perera
• 来源期刊: 世界骨科杂志
• 学科: 医学
• 关键词: ANTIMICROBIAL Coated IMPLANTS Antibiotic ANTISEPTIC NANO-SILVER Photoactive
• 年，卷（期）: sjgkzzywb_2016,（6）
• 页码范围: 361-369
• 页数: 9页
• 分类号: R

摘要

Infections can hinder orthopedic implant function and retention.Current implant-based antimicrobial strategies largely utilize coating-based approaches in order to reduce biofilm formation and bacterial adhesion.Several emerging antimicrobial technologies that integrate a multidisciplinary combination of drug delivery systems,material science,immunology,and polymer chemistry are in development and early clinical use.This review outlines orthopedic implant antimicrobial technology,its current applications and supporting evidence,and clinically promising future directions.