4-61 Effects of CORM-3 on Developmental Toxicity Induced by Ionizing Radiation in Zebrafish Embryos

• 作者: Si Jing Zhang Hong Zhou Rong
• 来源期刊: 中国科学院近代物理研究所和兰州重离子研究装置年报：英文版
• 学科: 物理学
• 年，卷（期）: 2016,（1）
• 页码范围: 187-188
• 页数: 2页
• 分类号: O4

摘要

CORM-3 is a water-soluble CO-releasing carbonyl complex.A low concentration of CO has been proved to be involved in the protection against cell death and oxidative injury,anti-inflammatory and anti-apoptotic effects,control of cell proliferation,tolerance of organ transplantation and neurotransmission[1].Using a zebrafish model,this study was designed to investigate the protective effects of CORM-3 on the developmental toxicity in zebrafish embryos induced by ionizing radiation with different linear energy transfer(LET).