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摘要:
Many factors, such as environmental, microbial and endogenous stress, antigen localization, can trigger the immunological events that affect the ending of the diverse spectrum of ocular disorders. Significant advances in understanding of immunological and molecular mechanisms have been researched to improve the diagnosis and therapy for patients with ocular inflammatory diseases. Some kinds of ocular diseases are inadequately responsive to current medications;therefore, immunotherapy may be a potential choice as an alternative or adjunctive treatment, even in the prophylactic setting. This article first provides an overview of the immunological and molecular mechanisms concerning several typical and common ocular diseases; second, the functions of immunological roles in some of systemic autoimmunity will be discussed; third, we will provide a summary of the mechanisms that dictate immune cell trafficking to ocular local microenvironment in response to inflammation.
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篇名 Ocular diseases: immunological and molecular mechanisms
来源期刊 国际眼科杂志:英文版 学科 医学
关键词 immunological mechanism ocular diseases systemic autoimmunity immune response CHEMOKINES
年,卷(期) 2016,(5) 所属期刊栏目
研究方向 页码范围 780-788
页数 9页 分类号 R77
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节点文献
immunological
mechanism
ocular
diseases
systemic
autoimmunity
immune
response
CHEMOKINES
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研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
国际眼科杂志:英文版
月刊
2222-3959
西安市友谊东路269号
出版文献量(篇)
2720
总下载数(次)
2
总被引数(次)
0
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