Effect of focal laser photocoagulation in eyes with mild to moderate non-proliferative diabetic retinopathy

• 作者: Chul Gu Kim Dong Won Lee Jong Woo Kim Jung Il Han Seong Hun Jeong Sung Won Cho Tae Gon Lee
• 来源期刊: 国际眼科杂志：英文版
• 学科: 医学
• 年，卷（期）: 2016,（10）
• 页码范围: 1439-1443
• 页数: 5页
• 分类号: R77

摘要

AIM:To report the effect of focal laser photocoagulation on both the severity of hard exudates(HEs) and the rate of disease progression in eyes with mild to moderate non-proliferative diabetic retinopathy(NPDR).METHODS: We retrospectively reviewed the medical records of 33 patients(60 eyes) who had been diagnosed with mild to moderate NPDR between January 2006 and December 2012.The patients were divided into 2 groups:Group A(38 eyes in 20 patients treated using focal laser photocoagulation) and Group B(treated without laser photocoagulation).We also reviewed the best corrected visual acuity measurements,and the fundus photographs taken at both baseline and follow-up visits. RESULTS: In Group A,HE severity grade had decreased significantly from baseline to the final visit(P <0.05),but this was not the case in Group B(P =0.662).The cumulative probabilities of retinopathy progression at 5y were 26% in Group A and 30% in Group B.KaplanMeier survival curves showed no significant difference between the groups with regard to retinopathy progression(P =0.805).CONCLUSION: Focal laser photocoagulation reduced the levels of HEs in eyes with mild to moderate NPDR.However,the treatment was not able to decelerate the progression of DR.