Lung microbiome in healthy and diseased individuals

• 作者: Inna Komkova Oksana Zolnikova Petr Tkachenko Vladimir Ivashkin Yulia Evsyutina
• 来源期刊: 世界呼吸病学杂志
• 学科: 医学
• 关键词: MICROBIOME Respiratory diseases PROBIOTICS PREBIOTICS Gut-lung axis SYNBIOTICS
• 年，卷（期）: 2017,（2）
• 页码范围: 39-47
• 页数: 9页
• 分类号: R

摘要

The data on quantitative and qualitative microbial composition of the respiratory tract of healthy individuals revealed significant differences when compared with the microbiota of patients suffering from respiratory diseases.Possible etiological role of microbiota in pulmonary diseases as well as drug resistance development is of profound interest nowadays.Numerous studies have provided evidence confirming the relationship between gut microbiome and those of lungs.This relationship could explain how changes in the microbial communities in one organ may lead to pathological changes in the other.Till date,some progress has been made in the study of the biological properties of probiotic bacteria,considering their modulating effect on inflammatory immune response.The use of probiotics which exhibits an immunomodulatory potential looks promising.