Preliminary Investigation on the Chemical Constituents and Antioxidant Activities of Two <i>Phellinus</i>Mushrooms Collected in Foshan

• 作者: Chunyan Wang Feng Zhu Weihong Lu Weijie Feng Xin Chen Zhaofeng Song
• 来源期刊: 有机化学国际期刊(英文)
• 学科: 医学
• 关键词: Mushroom PHELLINUS sp. PHELLINUS pini Chemical Constituent ANTIOXIDANT Activity
• 年，卷（期）: yjhxgjqkyw_2017,（1）
• 页码范围: 25-33
• 页数: 9页
• 分类号: R28

摘要

The Phellinus mushrooms have been known for its immunomodulatory, hypolipidemic, and anticancer activities. In the current work, the chemical constituents of two Phellinus mushrooms, Phellinus pini 141016# and Phellinus sp. 150802#, which were collected in Foshan city, Guangdong province, were investigated preliminarily by pre-test tube method and by comparison with the known natural compounds from Phellinus pini, and their antioxidant activities were evaluated by the biochemical assay of hydroxyl and 2,2-diphenyl-1-pricylhydrazyl (DPPH) radicals scavenging activity in vitro. The results show that both the two Phellinus mushrooms contain phenolics, alkaloids, lactones, steroids and terpenoids, and have potent antioxidant activities. The IC50 values of DPPH radicals and hydroxyl radicals for Phellinus pini 141016# were 74.37 μg/mL and 59.69 μg/mL, respectively, and the IC50 values of DPPH radicals and hydroxyl radicals for Phellinus sp. 150802# were 98.95 μg/mL and 165.47 μg/mL, respectively. They are comparable to the antioxidant activity of the standard antioxidant ascorbic acid.