Efficacy of Intravenous Immunoglobulin in a Case of Emanuel Syndrome

• 作者: Hironao Numabe Hisashi Kawashima Kazushi Agata Shigeo Nishimata Soken Go Yasuyo Kashiwagi Yasuyuki Morishima
• 来源期刊: 儿科学期刊(英文)
• 学科: 医学
• 关键词: Emanuel SYNDROME IVIG
• 年，卷（期）: 2017,（1）
• 页码范围: 32-36
• 页数: 5页
• 分类号: R5

摘要

We report a case of a male patient with Emanuel syndrome (ES) with multiple systemic malformations. He had frequent recurrent seizures and infectious diseases after six months. Because the level of immunoglobulin (IgG) was below the normal range for his age, he was administered intravenous immuno-globulin (IVIG) whenever infection occurred. As he grew up, the frequency of infections and seizures were reduced after IVIG therapy. Although the mechanism was not identified, IVIG might be effective for not only recurrent infections, but also for reducing recurrent seizures.