Study of Diffusion through the Skin of Coated L-Ascorbic Acid by Fluid Bed Technology

• 作者: Capablanca Lucía Ferrándiz Marcela
• 来源期刊: 封装与吸附期刊(英文)
• 学科: 化学
• 关键词: pH DEPENDENT POLYMER L-Acid Ascorbic DIFFUSION Fluid BED
• 年，卷（期）: 2017,（2）
• 页码范围: 75-82
• 页数: 8页
• 分类号: O6

摘要

Coating protects substances such as L-ascorbic acid from natural processes like oxidation. In this study, L-ascorbic acid was coated by fluid bed technology. A pH-dependent polymer was used as a coating material in order to release L-ascorbic acid (dissolution above pH 5.5) under conditions closest to the skin’s natural condition. Different techniques were used to determine the coating (SEM and size distribution) and to evaluate the percentage of coated L-ascorbic acid and its diffusion through the skin.