A Patient with Malignant Spinal Epidural Lymphoma with Initial Rapidly Aggravating Paraplegia

• 作者: Akihito Wada Hideyuki Aoki Hiroshi Takahashi Keiji Hasegawa Shintaro Tsuge Taihei Go Yasuaki Iida Yuichiro Yokoyama Yuri Akishima-Fukasawa
• 来源期刊: 矫形学期刊(英文)
• 学科: 医学
• 关键词: MALIGNANT LYMPHOMA EPIDURAL Mass PARAPLEGIA THORACIC SPINE
• 年，卷（期）: 2017,（3）
• 页码范围: 90-97
• 页数: 8页
• 分类号: R73

摘要

We report the case of a 51-year-old female with rapid neurological deterioration as an initial presentation of non-Hodgkin’s lymphoma. Paraplegia occurred suddenly after a 4-day history of weakness and numbness of the lower extremity. MRI revealed a dorsal epidural mass from T10 to T11 that compressed the spinal cord. There was neither bone destruction nor a paravertebral mass. Emergency decompressive laminectomy and tumor resection were performed. Histological analysis of the surgical specimen indicated diffuse large B cell lymphoma. The clinical stage was IV on CT and complete remission was achieved by subsequent chemotherapy. Spinal cord compression occurs in the course of non-Hodgkin’s lymphoma in 0.1% - 6.5% of cases, but this situation usually develops in the late phase with bone destruction and/or a paravertebral mass. Cord compression and especially the severe symptoms such as paraplegia are rare as the initial presentation of lymphoma.