Clinical Case: About a Probable Case of Post-Transfusion Purpura in a Homozygous Sickle Cell

• 作者: Buscotin Eugenie Fenomama Jocia Fenomanana Maminirina Sonia Rakoto Alson Olivat Aimé Rakotoniaina Andriamiarimbol Irène Rasamindrakotroka Andry
• 来源期刊: 临床医学病理报告(英文)
• 学科: 医学
• 关键词: Post TRANSFUSION PURPURA THROMBOCYTOPENIA SICKLE Cell Disease Bumps
• 年，卷（期）: 2017,（6）
• 页码范围: 196-199
• 页数: 4页
• 分类号: R5

摘要

Alloimmunization to platelet antigens exposes to a serious immunological incident. We report a probable case of a post-transfusion purpura from homozygous sickle cell child alloimmunized against platelet antigen. We detail the challenges of alloantibody identification and transfusion management. These challenges are due to the lack of laboratory techniques for typing HLA and HPA system and the use of leukocyte-depleted (filtered) blood products.