Solvent- and Catalyst-Free Microwave-Assisted Decarboxylation of Malonic Acid Derivatives

• 作者: Fanny Araceli Cabrera-Rivera Jaime Escalante Luis Gabriel Hernández-Vázquez Maria Durán-Galván Patricia Flores-Sánchez
• 来源期刊: 绿色与可持续化学(英文)
• 学科: 化学
• 关键词: Microwave DECARBOXYLATION Malonic Acid DERIVATIVES SOLVENT-FREE CATALYST-FREE Green Chemistry
• 年，卷（期）: 2017,（4）
• 页码范围: 270-280
• 页数: 11页
• 分类号: O6

摘要

It has been found that microwave assisted decarboxylation of malonic acid derivatives can be achieved under solvent-free and catalyst free conditions. This new method produces the corresponding carboxylic acid in a pure manner and with a high yield in a very short reaction time: 3 - 10 min. In general terms, the condition under which this reaction is carried out accelerates the decarboxylation significantly of a series of disubstituted malonic acid derivatives, and makes this new process efficient, easy and environmentally friendly.