In vitro Antibacterial Efficacy of <i>Bidens pilosa</i>, <i>Ageratum conyzoides</i>and <i>Ocimum suave</i>Extracts against HIV/AIDS Patients’ Oral Bacteria in South-Western Uganda

• 作者: Ambrose Amamchukwu Akunne Anthonia Shodunke Chukwudi Onyeka Okonkwo Ezera Agwu Frederick Byarugaba Jennifer Chibuogwu Ebosie Joseph Obiezu Chukwujekwu Ezeonwumelu Julius Kihdze Tanayen Keneth Iceland Kasozi Muhammad Ntale Onokiojare Ephraim Dafiewhare Steve Okwudili Ogbonnia
• 来源期刊: 药理与制药(英文)
• 学科: 医学
• 关键词: ANTIBACTERIAL EFFICACY BIDENS Pilosa Ageratum Conyzoides OCIMUM Suave Oral Bacteria HIV/AIDS Uganda
• 年，卷（期）: 2017,（9）
• 页码范围: 306-323
• 页数: 18页
• 分类号: R28

摘要

The objective of the study was to determine the antibacterial efficacy of Bidens pilosa Aqueous (BPA), Bidens pilosa Ethanolic (BPE), Ageratum conyzoides Aqueous (ACA), Ageratum conyzoides Ethanolic (ACE), Ocimum suave Aqueous (OSA) and Ocimum suave Ethanolic (OSE) extracts on HIV/AIDS patients’ oral bacteria. Healthy green leaves of the plants were collected in Ishaka Uganda, processed and portions separately extracted with hot distilled water and cold ethanol. The susceptibility, MIC and MBC of each extract were determined using standard protocols. The bacteria had significant (p Bidens pilosa, Ageratum conyzoides and Ocimum suave on oral lesions of HIV/AIDS patients made by traditional healers and local people in South-Western Uganda. We recommend a detailed study of structural identities and activities of the active antibacterial principle(s) in these plants for possible new drug entities and verification of the interactive effects of the principle(s) with ARVs and cotrimoxazole used daily by HIV/AIDS patients.