Recently,New England Journal of Medicine published an article by the famous hand surgery specialists,Yudong Gu. The important medical achievements of Gu’s team include transposition of C7 nerve root of the unaffected side on the upper limbs in stroke hemiplegia,changing the brain central dominance region,and rebuilding the function of hands with spastic paralysis. These achievements are admirable because worldwide medical problems,such as stroke sequela hemiplegia,require long-term arduous efforts for any progress to be made. Any result that improves the survival quality of patients has significant social value. Their success has enabled me to feel that I am no longer alone in my years of exploration,and I am grateful to them from the bottom of my heart. At this time,I am reminded of the 40 years of my experience in this field. It has taken the efforts of many people to make this happen: Limb sequelae of stroke,especially spasmodic paralysis of upper limbs,often result in patients losing their ability to self-care,which can cause a great burden to their family and society.The need to rebuild and improve functions in such patients is urgent.