Serum Vitamin D Levels and Severity of Liver Dysfunction in Cirrhotic Patients

• 作者: Abbas Ghasemi Baran Parhizkar Farshad Sheykhesmeeili Kambiz Yazdanpanah
• 来源期刊: 临床医学国际期刊(英文)
• 学科: 医学
• 关键词: CIRRHOSIS VITAMIN D LIVER CHILD-PUGH
• 年，卷（期）: 2017,（6）
• 页码范围: 402-411
• 页数: 10页
• 分类号: R5

摘要

Background and objective: Cirrhosis affects hundreds of millions of patients all around the world. Vitamin D deficiency is frequently observed in chronic hepatic disease. Vitamin D level may be an important survival marker in advanced liver cirrhosis. Material and Methods: The study is a sectional one of the descriptive-analytical type, where 90 of the patients with hepatic cirrhoses were selected with census sampling method. In all the cirrhotic patients, for diagnosis in clinical findings, the serological marker, autoantibodies were stable;biochemical endoscopy and imaging were the histological evidence and examinations and were then analyzed by SPSS version 22 software. Results: Based on the study, from the aspect of Child-Pugh classification, the highest vitamin D levels had the highest value in Child-Pugh class A with a frequency of 13 (43%) in the form of insufficiency, and had the highest value in Child-Pugh class B and C in the form of slight deficiency. Conclusion: It was specified based on the results obtained from the research that different vitamin D levels and liver failure severity have a significant relationship with each other (p < 0.05) in patients suffering from hepatic cirrhosis, such that the serum vitamin D level decreases as liver failure severity increases.