Effects of Gaseous Drinks in Wistar Rats Esophagus

• 作者: Daniel Almeida da Costa Joice Meire Rodrigues Lamara Laguardia Valente Rocha Larissa Menezes Viana Braga Marcelli Eliotério Gaspar Marcus Vinicius de Mello Pinto Nayara Barbosa Bicalho Rebeca Nogueira Falc?o Santos Suelen Gaudino Moura Thiago Dornelas de Oliveira
• 来源期刊: 生物科学与医学(英文)
• 学科: 医学
• 关键词: SOFT DRINKS CONSUMPTION INFLAMMATION CARBONATE Beverages
• 年，卷（期）: 2017,（5）
• 页码范围: 32-43
• 页数: 12页
• 分类号: R73

摘要

The consumption of beverages and processed foods, mainly soft drinks, has been incorporated into the usual diet of children, adolescents and adults frequently in recent years. The present study aimed to study the effects of carbonated drinks on Wistar rats, based on the macroscopic and histological morphology of the esophagus. Fifteen Wistar rats were divided into three groups: control group;group fed with ration and cola-type refrigerant ad libitum and group fed with ration and gas industrialized water ad libitum, for a trial period of 90 days. For histopathology and morphology, the esophagus was removed, prepared in slides and stained with hematoxylineosin. Images of the sections were captured for analysis and classification of the inflammatory infiltrate. For morphometry, ten grid fields of 100 points were evaluated in the 40x eyepiece, totaling 3000 points per animal. The results demonstrate that the refrigerant treatment induced the following structural changes in the rats: significant reduction of weight in relation to the control group;inflammatory infiltrate predominantly diffuse mild to moderate and tissue edema. The rats treated with carbonated water had similar results to the control, besides signs of healing and tissue repair.