Cutaneous Vasculitis with Renal Impairment in Octogenarian

• 作者: Bruna Sande Miguel Daniel Almeida da Costa Jair Baptista Miguel Lívia Cristina de Melo Pino Nayrton Kalys Cruz dos Anjos Paola Stephanie Azevedo de Sá Sebasti?o Celio Horta Coelho Filho Thiago Sande Miguel Vinicius Sande Miguel Vitor Araújo Goulart
• 来源期刊: 生物科学与医学(英文)
• 学科: 医学
• 关键词: PURPLE Henoch-Sch?nlein VASCULITIS Renal ELDERLY Case Report
• 年，卷（期）: 2017,（6）
• 页码范围: 37-45
• 页数: 9页
• 分类号: R5

摘要

Henoch-Schönlein purpura is a vasculitis of small vessels, characterized by tissue deposition of IgA, affecting predominantly the skin, intestine, joints and kidneys. It mainly affects the pediatric age group, especially from 2 to 11 years old. Most often, it is preceded by episode of upper airway infection from days to weeks. The most common clinical manifestations are purpuric cutaneous lesions located in the lower limbs and buttocks, abdominal pain in colic, nausea, vomiting, diarrhea, in addition to arthralgia/arthritis, usually with spontaneous resolution. Renal impairment usually manifests with hematuria and proteinuria, and renal function may also be impaired. The case described refers to a female patient, 86 years old, with a previous history of infection of the upper airways, followed by purpura in the lower limbs and renal impairment: serum creatinine 3.1 mg/dL (N 0.5 - 1.2 mg/dL);glomerular filtration rate 15 ml/min (N > 60 ml/min);urea 118 mg/dL (N önlein purpura in an atypical age group, with significant renal impairment, improvement only with conservative treatment, thus avoiding the use of immunosuppressants and the risks of immunosuppression and toxicity related to such drugs.