Evaluation of Adverse Events Following Immunization against Rotavirus Regardless of Recommended Age Restriction

• 作者: Ana Elena Limón-Rojas Cory Handelsman Dalila Ramos-López Freya Helena Campos-Romero Gabriela Cardoso-Yah Irina Jeanette Bercholc-Urinowsky Jesus Reyna-Figueroa Ricardo Platón Vazquez-Alvarado
• 来源期刊: 生物科学与医学(英文)
• 学科: 医学
• 关键词: ROTAVIRUS VACCINATION Age RESTRICTION ADVERSE REACTION
• 年，卷（期）: 2017,（8）
• 页码范围: 78-82
• 页数: 5页
• 分类号: R73

摘要

Introduction: Mild and moderate Adverse Events Following Immunization (AEFI) against Rotavirus has not received much attention when the vaccine is administered regardless of recommended age restriction. Objectives: To describe the behavior of mild and moderate AEFI in immunized subjects against Rotavirus, in who age restriction period had not been considered. Methods: A case-control study in which we included immunized patients with monovalent oral vaccine against rotavirus and divided them into two groups: 1) Infants who received RV1 vaccine without considering the recommended period, and 2) Infants who were vaccinated with the recommended schedule. Results: From the total doses, 143/1894 (7.5%) were administered outside the restriction period. The most frequent AEFIs with the first dose were purpura, polypnea, and rhinorrhea;For the second dose: purpura, bloody stools, irritability and rhinorrhea. Conclusions: This study shows the benefits from vaccination regardless of age restriction are more beneficial compared to the possible risks of AEFI.