Cap polyposis refractory to Helicobacter pylori eradication treated with endoscopic submucosal dissection

• 作者: Akira Andoh Hiromitsu Ban Masahide Fukuda Masaki Murata Mitsushige Sugimoto Osamu Inatomi Ryoji Kushima Shigeki Bamba Taketo Otsuka Toshiro Nakata
• 来源期刊: 世界胃肠内镜杂志：英文版（电子版）
• 学科: 医学
• 年，卷（期）: 2017,（10）
• 页码范围: 529-534
• 页数: 6页
• 分类号: R57

摘要

Cap polyposis is a rare intestinal disorder. Characteristic endoscopic findings are multiple inflammatory polypoid lesions covered by caps of fibrous purulent exudate. Although a specific treatment has not been established, some studies have suggested that eradication therapy for Helicobacter pylori(H. pylori) is effective. We report a case of a 20-year-old man with cap polyposis presenting with hematochezia. Colonoscopy showed the erythematous polyps with white caps from the sigmoid colon to rectum. Histopathological findings revealed elongated, tortuous, branched crypts lined by hyperplastic epithelium with a mild degree of fibromusculosis in the lamina propria. Although H. pylori eradication was instituted, there was no improvement over six months. We then performed en bloc excision of the polyps by endoscopic submucosal dissection(ESD), which resulted in complete resolution of symptoms. ESD may be a treatment option for cap polyposis refractory to conservative treatments. We review the literature concerning treatment for cap polyposis and clinical outcomes.