Effects of Oral Administration of Camel Milk and Urine on Gut Microbiota: Biochemical and Microbiological Profiling in Rats

• 作者: Manal S. Alenini Samah O. Noor
• 来源期刊: 美国分子生物学期刊(英文)
• 学科: 医学
• 关键词: Camal Milk URINE GUT Microbioa HPLC DGGE
• 年，卷（期）: 2018,（1）
• 页码范围: 1-12
• 页数: 12页
• 分类号: R5

摘要

Human intestinal tract contained a diverse number of microbial communities which performed a significant role in human health. The presence of gut microbiota was affected mainly by diet. Camel milk is the source of nutrition and provides all the essential nutrients for growth. It has great significance in the treatment of liver, spleen, and anemic infections. Camel urine has also many medical advantages. In this study we examined the effect of camel milk and urine and a mixture of both (milk + urine) on the growth of Gut microbiota using an in vivo animal model. Fresh fecal samples were collected before and after administration of the tested materials. After that, the microbial analysis was conducted via culturing, denaturing gradient gel electrophoresis and metabolic analysis via high-performance liquid chromatography (HPLC). The result indicated that the numbers of bacterial groups were increased after the first dose. Coliform group have significant increase when given a mix of milk and urine compared to control group with P < 0.05. Bifidobacterium group have significant increase in their number in the Milk and Mix groups compared to control group with P < 0.05. The concentration of Short-chain fatty acids in fecal samples was increased in Milk and Mix groups compared to control group. In conclusion, drinking camal milk, urine or a mix of both increased the growth of Gut microbiota.