Genetically encoded neural activity indicators

• 作者: Fang Luo Ji Hu Minmin Luo Yin Wei Ziyue Wang
• 来源期刊: 临床转化神经医学(英文版)
• 学科: 生物学
• 年，卷（期）: 2018,（1）
• 页码范围: 1-15
• 页数: 15页
• 分类号: Q42

摘要

Recent years have witnessed the fascinating development of imaging approaches to studying neural activities; this progress has been based on an influx of ideas and methods from molecular biology and optical engineering. Here we review the design and application of genetically encoded indicators for calcium ions, membrane potential and neurotransmitters. We also summarize common strategies for the design and optimization of genetically encoded neural activity indicators.