Endoscopic retrograde cholangiopancreatography-induced and non-endoscopic retrograde cholangiopancreatographyinduced acute pancreatitis:Two distinct clinical and immunological entities?

• 作者: Goran Hauser Goran Poropat Ivana Mikolasevic Ivana Plavsic Ivana Zitini
• 来源期刊: 世界胃肠内镜杂志：英文版（电子版）
• 学科: 医学
• 关键词: Acute PANCREATITIS ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY Post ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY PANCREATITIS
• 年，卷（期）: 2018,（10）
• 页码范围: 259-266
• 页数: 8页
• 分类号: R

摘要

Acute pancreatitis(AP)is common gastrointestinal disease of varied aetiology.The most common cause of AP is gallstones,followed by alcohol abuse as an independent risk factor.With the increased need for invasive techniques to treat pancreatic and bile duct pathologies such as endoscopic retrograde cholangiopancreatography(ERCP),AP has emerged as the most frequent complication.While severe AP following ERCP is rare(0.5%),if it does develop it has a greater severity index compared to non-ERCP AP.Development of a mild form of AP after ERCP is not considered a clinically relevant condition.Differences in the clinical presentation and prognosis of the mild and severe forms have been found between non-ERCP AP and postendoscopic pancreatitis(PEP).It has been proposed that AP and PEP may also have different immunological responses to the initial injury.In this review,we summarise the literature on clinical and inflammatory processes in PEP vs non-ERCP AP.