Highly-Controllable Imprinted Polymer Nanoshell on the Surface of Silica Nanoparticles for Selective Adsorption of 17<i>β</i>-Estradiol

• 作者: An Wang Bo Song Chun Wang Xiaozhen Chen Xue Fu
• 来源期刊: 封装与吸附期刊(英文)
• 学科: 化学
• 关键词: Surface-Imprinting Core-Shell Nanoparticle Selective Adsorption 17Β-ESTRADIOL
• 年，卷（期）: 2018,（4）
• 页码范围: 210-224
• 页数: 15页
• 分类号: O6

摘要

A highly-controllable core-shell silica-MIPs absorbent by anchoring a MIPs layer to the surface of SiO2 nanoparticles via a surface molecular imprinting process was prepared. The templates were covalently modified with functional monomers to form precursor EstSi. The latter together with coupling reagent KH-570, were grafted onto the surface of SiO2 nanoparticles before polymerization, to ensure the quantity and quality of imprinted sites on the surface of the covalently attached matrix. The as-synthesized core-shell nanomaterials (SiO2@MIP2) were then evaluated for selective adsorption of 17β-estradiol (E2) with Raman spectra as detection method. The results indicate that SiO2@MIP2 can fast and selectively adsorb E2 from structural analogues, with detection limit of 0.01 μmol/l.