Computational Fluid Dynamics Analysis of Shroud Design on Hemodynamic Performance and Blood Damage in a Centrifugal Blood Pump

• 作者: Guangliang Pan Mingrui Fu Yu Chang
• 来源期刊: 工程与科学中的计算机建模(英文)
• 学科: 工学
• 关键词: Computational fluid dynamics(CFD) HEMODYNAMICS centrifugal BLOOD pump SHROUD design BLOOD DAMAGE THROMBOSIS HEMOLYSIS
• 年，卷（期）: 2018,（8）
• 页码范围: 199-213
• 页数: 15页
• 分类号: TK1

摘要

Patients with extracorporeal membrane oxygenation still suffer from high rates of complication that linked to the flow field within the blood pump.So it is essential to optimise the geometry of the pump.The specification of shroud design is arguably the necessary design parameter in the centrifugal pump.However,the hemodynamic performances of the different shroud designs have not been studied extensively.In this study,ten different shroud designs were made and divided into two groups as the different covering locations(A:Covering the blade leading edge,B:Covering the blade trailing edge).In every group,six shroud designs with the covering proportions of 0,1/5,2/5,3/5,4/5,1 were made.Detailed computational fluid dynamics(CFD)analyses were performed to investigate their effects on hemodynamics and hydraulic performance at the constant flow condition(4000 rpm,5 L/min).The percentage volumes of the scalar shear stress in specific threshold(τ<1 Pa:Thrombosis,τ>9 Pa:the destruction of von Willebrand factor,τ>50 Pa:Platelet activation,τ>150 Pa:Break of red blood)were used to compare the blood damage of the different shroud designs.Also,the modified index of hemolysis(MIH)were calculated based on a Eulerian approach for different pumps.CFD simulations predicted an increase in the pump head,hydraulic efficiency,a fraction of fluid volume with scalar shear stress values above a threshold(9 Pa,50 Pa,150 Pa)and MIH with increasing shroud covering proportions from 0 to 1 in the same covering location.Also,these above results were higher in group B than group A.This means that the risks of the hemolysis,thrombosis and bleeding increased as the rise of the covering proportion and they were higher in the pump whose shroud covers the blade trailing edge.