The Effects of Colostrum on Gastrointestinal Function and Related Diseases in Premature Infants: A Comprehensive Meta-Analysis of Randomized Controlled Trials

• 作者: Lanping Shi Rong Tang Xiaoyun Yao
• 来源期刊: 长江医药(英文)
• 学科: 医学
• 关键词: Colostrums ORAL INTERVENTION GASTROINTESTINAL Function META-ANALYSIS System Review
• 年，卷（期）: cjyyyw_2018,（4）
• 页码范围: 271-280
• 页数: 10页
• 分类号: R73

摘要

Aim: To systematically evaluate the effects of colostrum intervention on gas-trointestinal function and related diseases in premature infants. Methods: A randomized controlled trial was conducted in the Cochrane Library, PubMed, EBSCO, CINAHL, Embase, Medline, CBMDISC, CNKI, Wan Fang and VIP databases on the effects of colostrum and oral intervention on gastrointestinal function and related diseases in premature infants. Literature screening, quality evaluation and data extraction were conducted, and data analysis was conducted using Revman 5.3. Results: A total of 7 references were included, including 392 subjects. The combined results showed that: colostrum can effectively reduce the incidence of nosocomial infection [RR = 0.42, 95% CI (0.25, 0.73), P = 0.002]. Conclusion: Colostrums oral intervention can effectively reduce the incidence of nosocomial infection in premature infants. However, there was no advantage in feeding intolerance, necrotizing enters colitis and length of hospital stay.