The Antibacterial and Antioxidant Effect of <i>Salvadora persica</i>on Antibiotic Resistant Strains

• 作者: K. Ounine S. Hsaine T. Djassinra Z. Mammad
• 来源期刊: 美国植物学期刊(英文)
• 学科: 医学
• 关键词: Salvadora persica Pseudomonas aeruginosa Acinetobacter BAUMANNII and ENTEROBACTER CLOACAE Extract SOXHLET DPPH Antioxidant Ascorbic Acid
• 年，卷（期）: 2018,（7）
• 页码范围: 1478-1485
• 页数: 8页
• 分类号: R28

摘要

Many efforts have been devoted to studying the inhibitory effect of Salvadora persica (Miswak) on oral microorganisms. However, information regarding its antibacterial activity against other human pathogens is rare. Particularly, against Pseudomonas aeruginosa, Acinetobacter baumannii and Enterobacter cloacae. The purpose of this piece of work was to evaluate the antioxidant power and in vitro antibacterial activities of Salvadora persica extract against the three bacterial clinical isolates mentioned above. Therefore, the action of Salvadora persica extract on the three germs, studied via the aromatograms method, has given an inhibition zone 20, 18 and 14 respectively on Pseudomonas aeruginosa, Acinetobacter baumannii and Enterobacter cloacae. The methanol extract of Salvadora persica using Soxhlet has given an output of 19%. The antioxidant evaluation, which was performed using the DPPH (1,1-diphenyl-2-picryl-hydrazyl), free radical scavenging method, indicated that the methanol extract showed good antioxidant efficiency (IC50 = 15.47 mg/ml) compared to ascorbic acid with (IC50 = 0.097 mg/ml).