Effect of Warm Acupuncture on “Dinghui Acupoint” and “Heart Acupoint” in Traditional Mongolian Medicine on Behaviors and Hypothalamic Inflammatory Cytokines in Rats with Chronic Fatigue Syndrome

• 作者: Ling Shui Qin Si Shumei Bai Yingsong Chen
• 来源期刊: 医学科学进展杂志(英文)
• 学科: 医学
• 关键词: Warm acupuncture in TRADITIONAL MONGOLIAN Medicine Chronic fatigue syndrome (CFS) BEHAVIORS Cytokines
• 年，卷（期）: 2019,（2）
• 页码范围: 8-13
• 页数: 6页
• 分类号: R392-33

摘要

Objective: To observe the effects of warm acupuncture on “Dinghui Acupoint” and “Heart Acupoint” in Traditional Mongolian Medicine on behavior and hypothalamic inflammatory cytokines IL-1β, IL-6 and IFN-r in Rats with Chronic Fatigue Syndrome. Methods: SD rats were randomly divided into normal group, model group, warm acupuncture group and moxibustion positive control group. The latter three groups of rats were used to establish a model of rats with chronic fatigue syndrome (CFS) using a combination of physical fatigue and mental fatigue. When establishing the model of warm acupuncture group,“Dinghui Acupoint” and “Heart Acupoint” intervention was carried out;when establishing the model of moxibustion positive control group,“Zusanli Acupoint” intervention was carried out on both sides. Behavioral observations (body weight, exhaustive swimming time, tail suspension experiment, water maze) were performed before and after modeling. The hypothalamic inflammatory cytokines IL-1β, IL-6 and IFN-r were detected by ELISA method after warm acupuncture and moxibustion intervention. Results: After 21 days of modeling, the body weight of the rats in each group was significantly lower than that in the normal group, and there was a significant difference (P<0.01);Compared with the model group, the weight of the rats in the warm acupuncture group increased significantly, and there was a significant difference (P<0.01);Compared with the model group, the exhaustive swimming time of the rats in the warm acupuncture group was significantly prolonged, and there was a significant difference (P<0.01);Compared with the moxibustion group, the exhaustion time of the rats in the warm acupuncture group was relatively prolonged, and there was a significant difference (P<0.05);Compared with the normal group, the tail suspension time of the model group was significantly prolonged, and there was a significant difference (P<0.05);Compared with the model group, there was a significant difference in the duration of the suspen