Novel Cancer Treatment Using Targeted Delivery of Short-Lived Radiologically Activated Nanoparticles

• 作者: J.B.Leao P.L.Andrade
• 来源期刊: 健康科学:英文版
• 学科: 生物学
• 关键词: NANOPARTICLES NEUTRON activation IRRADIATION cancer metabolism WARBURG effect GLUTAMINE GLUCOSE
• 年，卷（期）: 2019,（1）
• 页码范围: 43-47
• 页数: 5页
• 分类号: Q

摘要

The goal of our preliminary study is to show that a minimal of overall body toxicity while maximizing the cancer tumor treatment may be achieved in a novel approach where minute amounts of coated nanoparticles may be radiologically activated prior to treatment and“coerce”tumor cells into readily absorb these nanoparticles.This targeted intracytoplasmic delivery of short-lived radiologically activated nanoparticles could provide less“whole-body”radiation dose while delivering a short lived potent tumor localized dose,along with their low toxicity may prove to be another tool in the treatment of diverse cancers.