Clinical, Pathological and Surgical Risk Factors Associated with Craniopharyngioma Recurrence: A Literature Review

• 作者: James Lubuulwa Juan Chen Kai Shu Sheng Wang Shengwen Liu Ting Lei Wei Jiang Zhuang Miao
• 来源期刊: 现代神经外科学进展(英文)
• 学科: 医学
• 关键词: CRANIOPHARYNGIOMA RECURRENCE Risk Factors SUBTOTAL RESECTION
• 年，卷（期）: 2019,（1）
• 页码范围: 61-77
• 页数: 17页
• 分类号: R73

摘要

Objective: This review article attempts to examine and provide an overview of the risk factors associated with craniopharyngioma recurrence. Methods: A literature review of articles relating to the recurrences of craniopharyngioma and the clinical, molecular prognostic indicators of recurrence and treatment outcomes was performed retrospectively. Results: A total of 107 studies which described specific risk factors related to craniopharyngioma recurrence were identified which included but not limited to 54 retrospective case series, 7 systematic reviews, 21 laboratory reports, 13 case reports and 12 literature reviews. Conclusion: Based on the evidence identified in this review, the risk factors for recurrence in craniopharyngioma management are interrelated in a complex way, and surgery with or without adjuvant radiotherapy is reported to be of long-term benefit, but a disparity in findings suggests no definitive consensus on the risk factors of craniopharyngioma recurrence. More high-quality research is needed.